Actropen INJ.
Original price was: ₦5,300.00.₦5,000.00Current price is: ₦5,000.00.
Actropen INJ: is indicated for treatment of the following infections, in adults and children (aged 3 months and over), when the causative organisms are known or suspected to be resistant to commonly used antibiotics:
Product Description: Meropenem Im/Iv Injection
Dosage: As prescribed by the Doctor.
PACK SIZE: 1 vial + WFI
CTN SIZE: 120
PRICE PER PACK.
1000000 in stock
Dosage & Administration
Adults
Usual dose
500 mg to 1 g by intravenous administration every 8 hours depending on type and severity of infection, the known or suspected susceptibility of the pathogen(s) and the condition of the patient.
Exceptions
1. Febrile episodes in neutropenic patients – the dose should be 1 g every 8 hour.
2. Meningitis – the dose should be 2 g every 8 hours.
As with other antibiotics, caution may be required in using meropenem as monotherapy in critically ill patients with known or suspected Pseudomonas aeruginosa lower respiratory
Regular sensitivity testing is recommended when treating Pseudomonas aeruginosa infection.
Actropen should be given as an intravenous bolus injection over approximately 5 minutes or by intravenous infusion over approximately 15 to 30 minutes,
Dosage schedule for adults with impaired renal function
Dosage should be reduced in patients with creatinine clearance less than 51 mL/min, as scheduled below.
| Creatinine Clearance | Dose (based on unit doses of 500 mg, 1 g, 2 g) | Frequency |
| 26 to 50 | One-unit dose | Every 12 hours |
| 10 to 25 | One-half unit dose | Every 12 hours |
| <10 | One-half unit dose | Every 24 hours |
Meropenem is cleared by hemodialysis. If continued treatment with Actropen is necessary, it is recommended that the unit dose (based on the type and severity of infection) is administered at the completion of the hemodialysis procedure to restore therapeutically effective plasma concentrations.
There is no experience with peritoneal dialysis.
Use in adults with hepatic insufficiency
No dosage adjustment is necessary in patients with impaired hepatic metabolism,
Elderly patients
No dosage adjustment is required for the elderly with normal renal function or creatinine clearance values above 50 mL/min.
Children
For infants and children over 3 months and up to 12 years of age the recommended intravenous dose is 10 to 40 mg/kg every 8 hours depending on type and severity of infection, the known or suspected susceptibility of the pathogen(s) and the condition of the patient. In children over 50 kg weight, adult dosage should be used.
Exceptions
1. Febrile episodes in neutropenic patients – the dose should be 20 mg/kg every 8 hours.
2. Meningitis – the dose should be 40 mg/kg every 8 hours.
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