Timitol
Timitol eye drops are indicated for the reduction of elevated intraocular pressure, patients with ocular hypertension, patients with chronic open angle glaucoma, aphakic patients with glaucoma, some patients with secondary glaucoma, patients with narrow angles and a history of spontaneous or iatrogenically-induced narrow.
Therapeutic Class
Dosage Form & Composition
Drop : Each ml contains Timolol Maleate BP Eq to Timolol 0.5%w/v Benzalkonium chloride NF 0.01% w/v (As preservative) Pack Size: PRESENTATION: 5 ml/10 ml bottle.
Indications
Timolol maleate eye drops are indicated for the reduction of elevated intraocular pressure, patients with ocular hypertension, patients with chronic open angle glaucoma, aphakic patients with glaucoma, some patients with secondary glaucoma, patients with narrow angles and a history of spontaneous or iatrogenically-induced narrow.
Contra-indications
CONTRA-INDICATIONS: Hypersensitivity to timolol maleate, or any of the other ingredients of this preparation. Particular caution should be exercised with patients suffering from the following: asthma, bronchitis, chronic respiratory diseases, second and third degree heart block and sinus bradycardia less than 50 per minute, peripheral vascular diseases and Raynaud’s phenomenon. Use in Pregnancy: Safety in pregnancy has not been established. Nursing mothers: Timolol maleate is detectable in human milk.
Adverse Effects
SIDE-EFFECTS AND SPECIAL PRECAUTIONS: Side-effects: Timolol maleate eye drops are usually well tolerated, the following adverse reactions have been reported. Aphakic cystoid’ macular oedema has been reported, although a.causal relationship to timolol maleate eye drops has not yet been established. . Eyes: Signs and symptoms of ocular irritation, including conjunctivitis, blepharitis and keratitis and a decrease in corneal sensitivity, have been reported. Visual’ disturbances including refractive changes (due to withdrawal of miotic therapy in some cases), diplopia and ptosis have been reported. Cardiovascular: Bradycardia, arrhythmia, hypotension, syncope, heart block, cerebrovascular accident, cerebral ischaemia, congestive heart failure, palpitation, cardiac arrest. . Respiratory: Bronchospasm (predominantly in patients with pre-existing bronchospastic disease), respiratory failure, dyspnoea. Body as a whole: Headache, asthenia, fatigue, chest pain. Integumentary: Hypersensitivity reactions, including localized and generalized rash, urticaria and alopecia. Nervous system: Dizziness, depression, increase in signs and symptoms of myasthenia gravis. Digestive: Nausea. Special Precautions: Although timolol maleate eye drops are applied topically, this medicine may be absorbed systemically. The same adverse effects found with systemic administration of beta adrenergic blocking agents may occur with topical administration.
Dosage & Administration
DOSAGE: Treatment can be initiated at one drop of 0,25% solution in each affected eye twice a day. If clinical response is not adequate, dosage may be changed to one drop of 0,50% solution in each affected eye twice a day. The use of TIMOLOL MALEATE eye drops is not recommended in premature infants or neonates. If the intraocular pressure is maintained at satisfactory levels, many patients can be maintained on once-a-day therapy. Because of naturally occurring diurnal variations in intraocular pressure, satisfactory response is best determined by measuring the intraocular pressure at different times during the day.
Reviews
There are no reviews yet.